There is a great promise in utilizing shallow paramagnetic luminescent defects such as NVcenters in conjunction with spin-labeled receptor proteins in biological and chemical sensing. One of the major challenges is the accurate and efficient placement of the receptor protein in the close vicinity of the luminescent center deposited within the host material. We analyze the FRET-driven functionalization of the surface, where the emission of the luminescent center serves as a donor of the excitation, and the photolabile group on the surface as the acceptor. The efficiency of biological detection with a combination of spin-labeled protein receptor and a shallow NV- center is considered.